VALPG - Clinical Valproic Acid, Free and Total,
Monitoring both total and free valproic acid levels in therapy. Low free valproic acid concentration relative to these ranges may suggest inadequate dosing. Find information about common, infrequent and rare side effects of Depakote Oral. Decreased Blood PlateletsSevere; Double VisionSevere; Fluid Retention In. Valproate VPA, and its valproic acid, sodium valproate, and valproate semisodium forms, are. Rifampin increases the clearance of valproate, leading to decreased valproate concentrations; Warfarin may increase warfarin concentration.
Is your patient's valproic acid dosage too
Valproic acid VPA often is used to treat mania in bipolar disorder, and it has a. levels, which could lead to unnecessary dosage adjustments or drug toxicity. Depakote Divalproex Sodium is a prescription anti-seizure drug used. Increasing levels of GABA may help prevent brain signals that lead to seizures. Depakote during pregnancy, your child is at risk for having a lower IQ.